Rex Saab 340B - file photo
The New South Wales-based regional airline has taken over the 'Gulf Run' from Skytrans.
It it was awarded to them in October 2014 by the Queensland Government after a competitive tender process.
The 'Gulf Run' consists of: Cairns - Normanton - Mornington Island - Burketown - Dommadgee - Mount Isa and return.
Rex will be operating 34-seat Saab 340Bs on the route.
Saab 340B VH-ZLQ had the honours of operating the first flight from Cairns, whilst fellow Saab 340B VH-ZLH was the first aircraft to operate the return flight.